Clinical and Electrocardiographic comparison of patients with primary Mitral Valve Prolapse Syndrome and control group

ABSTRACT: Mitral Valve Prolapse (WVP) in one of the commonest cardiac abnormalities. Echocardiography has generally been accepted as the diagnostic modality of choice, To assess the characteristic symptoms signs and electrocardiographic abnormalities of MVP results of prospective 500 age and sex matched healthy subjects without echocardiographic MVP (control subjects). The diagnostic criteria used were : Pansystolic or late leaflets of the mitral valve in M-Mode echocardiography with or without two - dimensional echocardiographic criteria (severe bowing of leaflet(s) on the parasternal long axis and four-chamber view).. A history of MVP in first degree relatives was more common in subjects with echocardiographic MVP (10.4%Vs 2%,P<0.001). Mid -systolic click (55.2% vs 3.2%,P<0.001) and late - systolic murmur(28.2% vs 0.4% ,P<0.001) were more common in subjects with as compared to those without echographic MVP but ,Systolic ejection murmur was common in contral group (24% vs 13% ,P<0.001). ST segment and wave changes supraventricular premature depolarization ,Paroxysmal supraventricular tachycardia atrial fibrillation ,atrial tachycardia ,ventricular tachycardia, WPW syndrome ,first degree A-V block ,Left ventricular hypertrophy LGL syndrome and RBBB occurred with similar ventricular hypertrophy with and without echocardiographic MVP on the resting 12-lead ECG,but ventricular premature depolarization was common in MVP (11% vs 7.4%,P<0.05) These results indicate that most patients with echocardiographic evidence of MVP have very high incidence of clinical features include symptome such as palpitation, auscultatory findings include mid-systolic click and late systolic murmur , dysrhythmia such as ventricular premature and a history of MVP in first degree relatives.